Dominant resistance and negative epistasis can limit the co-selection of de novo resistance mutations and antibiotic resistance genes
نویسندگان
چکیده
منابع مشابه
Co-selection of antibiotic and metal resistance.
There is growing concern that metal contamination functions as a selective agent in the proliferation of antibiotic resistance. Documented associations between the types and levels of metal contamination and specific patterns of antibiotic resistance suggest that several mechanisms underlie this co-selection process. These co-selection mechanisms include co-resistance (different resistance dete...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2020
ISSN: 2041-1723
DOI: 10.1038/s41467-020-15080-8